The CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS) seeks to address the increasing challenge of global warming and declining food security on agricultural practices, policies and measures through strategic, broad-based global partnerships. CCAFS is a collaboration among all 15 CGIAR Research Centers and coordinates with the other CGIAR research programs, led by the International Center for Tropical Agriculture (CIAT).

CCAFS brings together some of the world's best researchers in agricultural science, climate science, environmental and social sciences to identify and address the most important interactions, synergies and trade-offs between climate change and agriculture. The program is carried out with funding support from governments and aid agencies, both through the CGIAR Trust Fund and bilaterally. CCAFS aims to define and implement a uniquely innovative and transformative research program that addresses agriculture in the context of climate variability, climate change and uncertainty about future climate conditions.